RecruitingNot ApplicableNCT03894254

Predictive Factors of Autonomy Loss in Real-life Cohort

Predictive Factors Associated With Impairment in Functional Autonomy in a Regional Real-life Cohort of Patients With Alzheimer's Disease or Related Disorders (ADRD)

Sponsor

Hospices Civils de Lyon

Enrollment

5,400 participants

Start Date

Sep 9, 2020

Study Type

INTERVENTIONAL

Conditions

Memory Disorders

Summary

The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders. In absence of current curative treatment, the identification of the predictive risk factors of progression of the disease, evaluated through its main symptoms, represents a major stake of public health. The Investigators aim at developing a regional database, which includes the patient medical records on a prospective basis, in collaboration with the medical and administrative staff and with the University hospital computer science departments. The main objective is to study the predictive factors associated with change in functional autonomy level, measured every 6 to 12 months in centres across Region Auvergne Rhone-Alpes in France. The real-life study population will consist in about 5400 patients with ADRD. The inclusion period will be of 3 years, the length of follow-up of each patient will be of 10 years max for a total study length of 13 years.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial follows adults with memory problems over time to identify factors that predict loss of independence, aiming to help doctors better support patients and caregivers earlier. **You may be eligible if...** - You are 18 years or older - You have memory problems at any stage - You are seen at a memory or neurocognition clinic - You live at home or in residential housing (not an institution) **You may NOT be eligible if...** - You live in an institution - You are under legal protection that prevents consent - You have hearing or vision problems so severe they prevent testing Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERno intervention

This is study carried out in current practice. Patients are undergoing a medical examination in a memory center, with extensive and systematic evaluations for the study involving the following tests: IADL, DAD6, New AGGIR, NPI, and mini-Zarit) assessing the functions (autonomy, behavior and caregiver burden).