A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction
Impact of a Procalcitonin-based Algorithm on Quality of Management in Patients With Uncomplicated Adhesion-related Small Bowel Obstruction Assessed by Textbook Outcome: a Multicenter Cluster-randomized Open-label Controlled Trial. (ALPROC)
Centre Hospitalier Universitaire, Amiens
488 participants
Apr 1, 2019
INTERVENTIONAL
Conditions
Summary
Adhesion-related small bowel obstruction is a common digestive emergency that can be managed either conservatively or surgically. However, the choice between these two approaches can be difficult due to the absence of specific signs. The objective of this study is to evaluate the clinical impact of a procalcitonin-based algorithm.
Eligibility
Inclusion Criteria5
- Uncomplicated acute adhesion-related small bowel obstruction (ASBO)
- Adults
- Patients able to express consent
- Signed written informed consent form
- Covered by national health insurance
Exclusion Criteria13
- Disease-related criteria:
- Large bowel obstruction
- No previous abdominal surgery
- Signs of peritonitis or strangulation requiring emergency surgery)
- Obstruction within 4 weeks following previous surgery
- Ongoing or history of bowel cancer
- Ongoing or in history of inflammatory bowel disease
- History of abdominal radiotherapy
- Active infection
- Contraindication to contrast-enhanced CT scan
- Minors
- Patient deprived of liberty by administrative or judicial decision or placed under judicial protection (guardianship or supervision)
- Pregnancy or breastfeeding
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Interventions
clinical examination and procalcitonin assessment
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03905239