Cisplatin-based and Carboplatin-based Chemoradiation in Locoregionally Advanced Nasopharyngeal Carcinoma

This trial is comparing two chemotherapy drugs — cisplatin versus carboplatin — combined with radiation for locally advanced nasopharyngeal carcinoma (a cancer at the back of the nose), to see which causes fewer side effects while maintaining similar effectiveness. **You may be eligible if...** - You have a newly confirmed diagnosis of non-keratinizing nasopharyngeal carcinoma - Your cancer is locally advanced but has not spread to distant organs - You have adequate blood counts, liver, and kidney function - You are in reasonably good overall health **You may NOT be eligible if...** - Your cancer has spread to distant parts of the body - Your blood or organ function tests are below the required levels - You have previously received treatment for this cancer Talk to your doctor to see if this trial is right for you.