RecruitingNot ApplicableNCT03928431
Restoration of Microbiota in Neonates
Restoration of Microbiota in Neonates - a Randomized Controlled Trial
Sponsor
Karolinska Institutet
Enrollment
300 participants
Start Date
Jan 1, 2019
Study Type
INTERVENTIONAL
Conditions
Summary
The aim of the study is to examine the effect of exposure of cesarean section (CS) delivered neonates to a natural condition of birth, i.e. to the microbiota of the birth canal, on the acquisition of microbial genes during development of the microbiome at multiple body sites, immune system maturation and allergy risk in childhood
Eligibility
Min Age: 5 MinutesMax Age: 15 Minutes
Inclusion Criteria1
- Infants of healthy mothers with uncomplicated pregnancies at term, mothers of any ethnic or social background that can speak, read, and understand Swedish to the extent that they can consent in Swedish. An additional inclusion criterion for mothers in the CS groups is vaginal pH ≤ 4 at the time of birth.
Interventions
OTHERMaternal microbiota
See arm descriptions
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT03928431
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