RecruitingNCT03948438

Endoscopic Treatment for Zenker's Diverticulum

Clinical Outcome of Endoscopic Treatment for Zenker's Diverticulum


Sponsor

Istituto Clinico Humanitas

Enrollment

400 participants

Start Date

Jan 1, 2009

Study Type

OBSERVATIONAL

Conditions

Summary

Zenker's diverticulum (ZD) is a rare benign condition, due to an acquired sac-like outpouching of the mucosa and submucosa layers originating from the pharyngoesophageal junction. Endoscopic techniques like flexible endoscopic septum division (FESD) or per-oral endoscopic septotomy (POES), represent a minimally invasive alternative to surgery or to rigid endoscopic procedure to treat ZD. The goal of the research will be to evaluate the safety of the procedures and to measure Zenker-symptom severity in all patients treated by endoscopic procedures.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • patients with symptomatic ZD treated by endoscopic procedures

Exclusion Criteria1

  • pregnancy and breastfeeding

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Interventions

PROCEDUREEndoscopic septotomy

Patients will be placed in left lateral decubitus position, either in conscious sedation or under deep sedation with propofol or endotracheal intubation.The procedure will be performed with a flexible standard endoscope and started with initial endoscopic examination with suction of possible retained material insidethe diverticulum. An incision of the bridge between the ZD and the esophagus will be done (using one endoscopic procedure as POES or FESD or other)


Locations(1)

Humanitas Research Hospital

Rozzano, Italy

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NCT03948438


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