Smoking Cessation Behavioral Treatment Study
Neural Mechanisms Mediating Appetitive Regulation and Smoking in Nicotine Addiction
University of Missouri-Columbia
200 participants
Dec 19, 2019
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT). MORE is a behavioral therapy that integrates mindfulness training to modify reward processes. CBT is a therapy designed to help individuals understand how their thoughts and feelings influence their behaviors.
Eligibility
Inclusion Criteria5
- Age 18 and up
- English fluency as demonstrated in providing informed consent and the ability to independently follow directions in completing assigned assessments and tasks
- Functional vision (with corrective lenses as needed) to complete assigned assessments and tasks
- Current nicotine dependent smoker with a minimum smoking history of 2 years
- Interest in quitting smoking
Exclusion Criteria8
- Use of psychotropic (e.g. antiepileptic) medications in the past month
- Positive urine drug screen
- Presence of an untreated medical illness
- Current or past psychosis
- History of major neurological illness or head injury resulting in loss of consciousness
- And contraindication to MRI, including claustrophobia
- Among females, positive urine pregnancy test
- Inability or unwillingness of subject to give informed consent
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Interventions
MORE is a behavioral therapy that integrates mindfulness training to modify reward processes.
CBT is a therapy designed to help individuals understand how their thoughts and feelings influence their behaviors.
Locations(2)
View Full Details on ClinicalTrials.gov
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NCT03948893