A Clinicobiological Database in Metastatic Digestive Cancers

This study creates a database of clinical and biological information from patients with metastatic digestive cancers (including colon, rectal, small intestine, pancreatic, stomach, bile duct, and esophageal cancers). The data will be used to understand how these cancers behave and respond to treatment. **You may be eligible if...** - You are 18 or older - You have confirmed adenocarcinoma (a common cancer type) of the colon, rectum, small intestine, pancreas, stomach, bile duct, or esophagus that has spread (metastatic) - You are about to start your first or second line of chemotherapy or targeted therapy for metastatic disease - You have signed an informed consent form **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have already started treatment for metastatic disease - You are enrolled in a Phase I or II clinical trial that modifies standard treatment - You are not affiliated with a social security system (in France) Talk to your doctor to see if this trial is right for you.