RecruitingPhase 2NCT03989778

Vitamin D and Polycystic Ovarian Syndrome (PCOS)

Efficacy of Vitamin D Supplementation and Metformin Compared to Metformin Alone for Improvement in Follicle Size of Infertile Females With Polycystic Ovary Syndrome: a Randomized Open Label Trial


Sponsor

Aga Khan University

Enrollment

300 participants

Start Date

Feb 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Primary Objectives: To evaluate the efficacy of metformin and Vitamin D supplementation on serum insulin and serum androgen levels (Total testosterone, Steroid Hormone Binding Globulin, Free Androgen Index) levels compared metformin alone in infertile Poly cystic ovarian females of reproductive age group. Secondary Objectives: To measure change in endometrial thickness/number of follicles and follicular size by day 12 trans-vaginal ultrasound in the intervention group i.e. combination of metformin and vitamin D supplementation


Eligibility

Min Age: 18 YearsMax Age: 36 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Vitamin D for people with infertility, infertility, female, and other related conditions. The study is currently recruiting participants at 2 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGVitamin D

Vitamin D supplementation


Locations(2)

Dr Rehana Rehman

Karachi, Sindh, Pakistan

Dr Rehana Rehman

Karachi, Sindh, Pakistan

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NCT03989778


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