RecruitingNCT03991728

Alloplastic Total Temporomandibular Joint (TMJ) Replacement Registry

International, Multicenter, Prospective Registry to Collect Data of Patients Treated With Alloplastic Total Temporomandibular Joint (TMJ) Replacements


Sponsor

AO Innovation Translation Center

Enrollment

200 participants

Start Date

Oct 15, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

Prospective data will be collected in approximately 200 patients treated with an TMJ replacement. Patients will be followed up according to the standard (routine) for up to 5 years after the treatment. Data collection will include underlying disease, treatment details, functional and patient reported outcomes (PRO)s and anticipated or procedure-related adverse events (i.e. complications). This registry is designed to be able to assess the number of patients who refuse alloplastic total TMJ replacement. Therefore, the participating sites are asked to register all cases of refused TMJ replacements too.


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Age 18 years and or older
  • Patients requiring alloplastic total TMJ replacement
  • Informed consent obtained, i.e.:
  • Ability to understand the content of the patient information/informed consent form (ICF)
  • Willingness and ability to participate in the registry according to the Registry Plan (RP)
  • Signed and dated ethics committee (EC) / Institutional review board (IRB) approved written informed consent

Exclusion Criteria3

  • Recent history of substance abuse (i.e. recreational drugs, alcohol) that would preclude reliable assessment
  • Pregnancy or women planning to conceive within the study period
  • Participation in any other medical device or medicinal product study within the previous month that could influence the results of the present study

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Locations(23)

Hospital BP - A Beneficência Portuguesa de São Paulo

São Paulo, Brazil

Estetica Maxilofacial

Bogotá, Colombia

Rigshospitalet

Copenhagen, Denmark

Hannover Medical School

Hanover, Germany

University Hospital Leipzig

Leipzig, Germany

Klinikum der Johannes Gutenberg Universität Mainz

Mainz, Germany

Klinikum der LMU München

Munich, Germany

Sri Shankara Cancer Hospital and Research Center

Bangalore, India

All India Institute of Medical Sciences (AIIMS)

New Delhi, India

Erasmus Medisch Centrum

Rotterdam, Netherlands

Waikato DHB

Christchurch, New Zealand

Hutt Hospital

Lower Hutt, New Zealand

Mayo Hospital

Lahore, Pakistan

Wojewódzki Specjalistyczny Szpital Dziecięcy

Olsztyn, Poland

National Medical and Surgical Center named after N.I. Pirogov" of the Ministry of Healthcare of the Russian Federation

Moscow, Russia

Clinic for Maxillofacial Surgery, University of Belgrade

Belgrade, Serbia

King Edward VIII Hospital

Durban, South Africa

12 de Octubre University Hospital

Madrid, Spain

Falu Hospital

Falun, Sweden

Skåne University Hospital

Lund, Sweden

Karolinska University Hospital

Stockholm, Sweden

Uppsala University Hospital

Uppsala, Sweden

Universitätsspital Basel

Basel, Switzerland

View Full Details on ClinicalTrials.gov

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NCT03991728


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