RecruitingNCT04000061

Heart Failure-USB: Prediction and Progression

Sponsor

University Hospital, Basel, Switzerland

Enrollment

6,000 participants

Start Date

Jun 13, 2019

Study Type

OBSERVATIONAL

Conditions

Acute Coronary Syndrome Acute Heart Failure

Summary

This retrospective cohort study is to identify triggers of heart failure (HF) development and drivers of HF progression as well as the underlying cardiac disease (phenotype) to identify patients at risk and predict the clinical course of the disease. Data of patients who were hospitalized during the years 2010-2023 with acute coronary syndrome (ACS) and/ or with acute heart failure (AHF) will be collected and analyzed. In a subgroup cohort efficacy and safety of digoxin in patients with acute heart failure triggered by tachyarrhythmia will be evaluated.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is building a database to track and better understand two serious heart conditions — acute coronary syndrome (ACS, including heart attacks) and acute heart failure (AHF). The goal is to use clinical and biological information to help predict outcomes and understand how these diseases progress over time. **You may be eligible if...** - You are hospitalized with a primary diagnosis of acute coronary syndrome (heart attack or unstable angina) - You are hospitalized with acute heart failure as a primary or secondary reason for admission **You may NOT be eligible if...** - You have explicitly stated in writing that you do not want your clinical data used for scientific research Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERmedical chart review

data generated by medical review include Medical history, Medications at presentation, during hospitalization and at discharge, New York Heart Association (NYHA) class, Killip class, Electrocardiographic (ECG) data, echocardiographic data, Interventions (Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft (CABG), Implantable Cardioverter Defibrillator (ICD) implantation, Cardiac Resynchronization Therapy (CRT) Implantation), Outcome Information: all-cause death, HF hospitalizations

OTHERdata generated by direct IT export

data generated by direct IT export include Anthropometric data (age, sex, height, weight), Vital signs, Laboratory data

Locations(1)

Cardiology, University Hospital Basel

Basel, Switzerland

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NCT04000061

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