RecruitingNCT04000061

Heart Failure-USB: Prediction and Progression


Sponsor

University Hospital, Basel, Switzerland

Enrollment

6,000 participants

Start Date

Jun 13, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

This retrospective cohort study is to identify triggers of heart failure (HF) development and drivers of HF progression as well as the underlying cardiac disease (phenotype) to identify patients at risk and predict the clinical course of the disease. Data of patients who were hospitalized during the years 2010-2023 with acute coronary syndrome (ACS) and/ or with acute heart failure (AHF) will be collected and analyzed. In a subgroup cohort efficacy and safety of digoxin in patients with acute heart failure triggered by tachyarrhythmia will be evaluated.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Patients hospitalized with a primary diagnosis of ACS
  • Patients hospitalized with a primary or secondary diagnosis of AHF

Exclusion Criteria1

  • Existence of a documented statement of the patient against the scientific use of clinical data

Interventions

OTHERmedical chart review

data generated by medical review include Medical history, Medications at presentation, during hospitalization and at discharge, New York Heart Association (NYHA) class, Killip class, Electrocardiographic (ECG) data, echocardiographic data, Interventions (Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft (CABG), Implantable Cardioverter Defibrillator (ICD) implantation, Cardiac Resynchronization Therapy (CRT) Implantation), Outcome Information: all-cause death, HF hospitalizations

OTHERdata generated by direct IT export

data generated by direct IT export include Anthropometric data (age, sex, height, weight), Vital signs, Laboratory data


Locations(1)

Cardiology, University Hospital Basel

Basel, Switzerland

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NCT04000061


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