Acute Coronary Syndrome Clinical Trials

168 recruitingLast updated: June 17, 2026

There are 168 actively recruiting acute coronary syndrome clinical trials across 47 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2, Early Phase 1, Phase 1. Top locations include Beijing, Beijing Municipality, China, Seoul, South Korea, Jinan, Shandong, China. Updated daily from ClinicalTrials.gov.


Acute Coronary Syndrome Trials at a Glance

168 actively recruiting trials for acute coronary syndrome are listed on ClinicalTrialsFinder across 6 cities in 47 countries. The largest study group is Not Applicable with 53 trials, with the heaviest enrollment activity in Beijing, Seoul, and Jinan. Lead sponsors running acute coronary syndrome studies include Qilu Hospital of Shandong University, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), and Federico II University.

Browse acute coronary syndrome trials by phase

Treatments under study

About Acute Coronary Syndrome Clinical Trials

Looking for clinical trials for Acute Coronary Syndrome? There are currently 119 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Acute Coronary Syndrome trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Acute Coronary Syndrome clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 168 trials

Recruiting
Phase 4

Dual Antithrombotic Therapy With Dabigatran and Ticagrelor in Patients With ACS and Non-valvular AF Undergoing PCI

Atrial FibrillationAcute Coronary SyndromeAntithrombotic Therapy+1 more
Medical University of Gdansk1,194 enrolled1 locationNCT04695106
Recruiting
Not Applicable

Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation on Alleviating Major Depressive Disorder in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention:A Prospective, Double-Blind,Randomized Controlled Study

Depressive DisorderPercutaneous Coronary Intervention (PCI)Acute Coronary Syndrome (ACS)+5 more
Jing Han120 enrolled1 locationNCT07454070
Recruiting
Not Applicable

Oregano and Basil Leaves and Coronary Artery Disease

Acute Coronary SyndromesUnstable Angina (UA)
Shahid Beheshti University of Medical Sciences70 enrolled1 locationNCT07123181
Recruiting
Not Applicable

Predictive Value of Glycemic Parameters Measured With the FSL Pro iQ During ACS

Cardiovascular EventAcute Coronary SyndromeContinuous Glucose Measurement+1 more
University Hospital, Montpellier850 enrolled9 locationsNCT06014112
Recruiting
Phase 3

Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosis

Acute Coronary SyndromeTuberculosisPulmonary Hypertension (Diagnosis)
National University Hospital, Singapore150 enrolled6 locationsNCT05473520
Recruiting
Phase 1

The Pharmacokinetics and Pharmacodynamics Study of CG-0255 Besylate and Plavix® in Healthy Participants

Peripheral Arterial DiseaseRecent Myocardial InfarctionRecent Stroke+1 more
Shanghai CureGene Pharmaceutical Co., Ltd.136 enrolled1 locationNCT07619885
Recruiting
Not Applicable

TeleheartCR vs. Clinic-Based Cardiac Rehabilitation After Acute Coronary Syndrome

Myocardial InfarctionAcute Coronary Syndrome (ACS)
Columbia University250 enrolled1 locationNCT07541014
Recruiting
Phase 3

Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes

Acute Coronary Syndrome
Novartis Pharmaceuticals300 enrolled60 locationsNCT07102628
Recruiting

Artificial Intelligence Based Timing, Infarct Size and Outcomes in Acute Coronary Occlusion Myocardial Infarction

Coronary Arterial Disease (CAD)Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Azienda Ospedaliera di Bolzano1,500 enrolled1 locationNCT06910436
Recruiting
Not Applicable

Feasibility Study of a Digital Interactive Life-style Platform for Individuals After Rehabilitation

Acute Coronary SyndromeChronic Obstructive Pulmonary Disease (COPD)Fragility Fracture+1 more
Matthias Wilhelm, MD240 enrolled2 locationsNCT07597031
Recruiting
Phase 3

Analysis of Growth Differentiation Factor 15 (GDF-15), Mid Regional proAdrenomedullin (MR proADM), and Persepsin Levels in Patient in Acute Coronary Syndrome Patients With Pneumonia, With or Without Influenza Vaccination

PneumoniaCOPD, Chronic Obstructive Pulmonary Diseaseacute coronary syndromes (ACS)
University of Brawijaya60 enrolled1 locationNCT07604103
Recruiting
Not Applicable

Local And Systemic Macrophage Activation in Coronary and Peripheral Artery Disease

intermittent claudicationstable coronary artery diseaseAcute Coronary Syndromes+1 more
Maria Cecilia Hospital60 enrolled1 locationNCT07588295
Recruiting
Phase 3

Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty.

Coronary Artery DiseasePercutaneous Coronary InterventionAcute Coronary Syndromes+3 more
Cardiocentro Ticino355 enrolled1 locationNCT07582835
Recruiting

Florbetaben for Imaging of Vascular Amyloid

StrokeAcute Coronary SyndromeTransient Ischemic Attack+1 more
Ottawa Heart Institute Research Corporation30 enrolled1 locationNCT06091319
Recruiting
Not Applicable

Ticino Artificial InTelligence integrAtioN for Occlusion Myocardial Infarction

Myocardial Infarction (MI)Acute Coronary Syndrome (ACS)
Cardiocentro Ticino500 enrolled1 locationNCT07077057
Recruiting
Not Applicable

A Clinical Study on the Effect of Cardiopulmonary Function and Quality of Life in Patients With Acute Coronary Syndrome Complicated by Heart Failure by "Lying-Sitting-Standing" Sequential Baduanjin

ACS (Acute Coronary Syndrome)HF - Heart Failure
Xiling Qi65 enrolled1 locationNCT07486791
Recruiting
Not Applicable

Leave Nothing Behind Study Which Compares DCB With Bail Out BRS Versus BRS Strategy Alone

Percutaneous Coronary Intervention (PCI)Acute Coronary Syndrome (ACS)Drug-coated Balloon+1 more
Ceric Sàrl2,256 enrolled1 locationNCT07038408
Recruiting
Not Applicable

Orbital Atherectomy vs Intravascular Lithotripsy for the Treatment of Calcified Coronary Nodules (ORBIT-SHOCK).

Chronic Coronary SyndromeCoronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)+6 more
Spanish Society of Cardiology50 enrolled6 locationsNCT06736665
Recruiting
Not Applicable

Artificial Intelligence-Driven Medipixel Fractional Flow Reserve Versus Invasive Fractional Flow Reserve-Guided PCI Trial (AIM-FFR Trial)

Acute Coronary SyndromeCoronary Artery DiseaseChronic Coronary Syndrome
Samsung Medical Center2,100 enrolled23 locationsNCT07329699
Recruiting
Not Applicable

Positive Emotions Following Acute Cardiac Events

Physical InactivityAcute Coronary Syndrome
Massachusetts General Hospital280 enrolled1 locationNCT05412862