Acute Coronary Syndrome Clinical Trials

118 recruiting

Acute Coronary Syndrome Trials at a Glance

139 actively recruiting trials for acute coronary syndrome are listed on ClinicalTrialsFinder across 6 cities in 45 countries. The largest study group is Not Applicable with 37 trials, with the heaviest enrollment activity in Beijing, Seoul, and Jinan. Lead sponsors running acute coronary syndrome studies include Qilu Hospital of Shandong University, Federico II University, and Sohag University.

Browse acute coronary syndrome trials by phase

Treatments under study

About Acute Coronary Syndrome Clinical Trials

Looking for clinical trials for Acute Coronary Syndrome? There are currently 118 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Acute Coronary Syndrome trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Acute Coronary Syndrome clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 139 trials

Recruiting

Florbetaben for Imaging of Vascular Amyloid

StrokeAcute Coronary SyndromeTransient Ischemic Attack+1 more
Ottawa Heart Institute Research Corporation30 enrolled1 locationNCT06091319
Recruiting
Not Applicable

Orbital Atherectomy vs Intravascular Lithotripsy for the Treatment of Calcified Coronary Nodules (ORBIT-SHOCK).

Chronic Coronary SyndromeCoronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)+6 more
Spanish Society of Cardiology50 enrolled6 locationsNCT06736665
Recruiting
Phase 3

Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes

Acute Coronary Syndrome
Novartis Pharmaceuticals300 enrolled58 locationsNCT07102628
Recruiting
Not Applicable

Artificial Intelligence-Driven Medipixel Fractional Flow Reserve Versus Invasive Fractional Flow Reserve-Guided PCI Trial (AIM-FFR Trial)

Acute Coronary SyndromeCoronary Artery DiseaseChronic Coronary Syndrome
Samsung Medical Center2,100 enrolled23 locationsNCT07329699
Recruiting

Artificial Intelligence Based Timing, Infarct Size and Outcomes in Acute Coronary Occlusion Myocardial Infarction

Coronary Arterial Disease (CAD)Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Azienda Ospedaliera di Bolzano1,500 enrolled1 locationNCT06910436
Recruiting
Not Applicable

TeleheartCR vs. Clinic-Based Cardiac Rehabilitation After Acute Coronary Syndrome

Myocardial InfarctionAcute Coronary Syndrome (ACS)
Columbia University250 enrolled1 locationNCT07541014
Recruiting
Not Applicable

Positive Emotions Following Acute Cardiac Events

Physical InactivityAcute Coronary Syndrome
Massachusetts General Hospital280 enrolled1 locationNCT05412862
Recruiting
Not Applicable

A Study Evaluating the Vascular Healing and Neointimal Transformation at 1 Month After Implantation of BioFreedom™ Drug-coated Stents and the Xience Drug-eluting Stent System in Patients With Acute Coronary Syndrome and High Bleeding Risk Using Optical Coherence Tomography

Coronary Heart DiseaseAcute Coronary Syndrome
China National Center for Cardiovascular Diseases60 enrolled1 locationNCT07230847
Recruiting

Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) of Women With Acute Coronary Syndrome

Acute Coronary SyndromeGenetic PredispositionGender
IRCCS San Raffaele100 enrolled4 locationsNCT06441942
Recruiting
Not Applicable

Point-of-Care Troponin Testing in the Emergency Department

Acute Coronary Syndromes
KU Leuven1,552 enrolled1 locationNCT06845826
Recruiting

A Prospective, Single-center, Observational Study Aiming to Assess the Predictive Role of Flow Mediated Dilatation in Acute Coronary Syndromes, Combined With Echocardiographic and Biochemical Indices

Endothelial Function (FMD)Acute Coronary SyndromesFlow Mediated Dilation
Aristotle University Of Thessaloniki100 enrolled1 locationNCT06890013
Recruiting
Early Phase 1

Placebo-controlled Study of Single and Multiple Ascending Doses of UDP-003 in Healthy Human Participants and Patients

Atherosclerotic Cardiovascular DiseaseAcute Coronary Syndromes
Cyclarity Therapeutics, Inc.84 enrolled1 locationNCT06813339
Recruiting
Not Applicable

Revascularization Strategies in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome (NSTE-ACS) and Severe Coronary Artery Disease

Acute Coronary SyndromeMultivessel Coronary Artery Disease
American Heart of Poland1,000 enrolled7 locationsNCT01311323
Recruiting
Phase 4

MACT (Mono Antiplatelet and Colchicine Therapy) Prospective Multicenter Study

Acute Coronary Syndrome
CHA University490 enrolled9 locationsNCT06543082
Recruiting

Thrombus Aspiration and Pathology and OCT Study

Acute Coronary Syndrome
Fujita Health University200 enrolled1 locationNCT07151976
Recruiting

Acute Myocardial Infarction: Prognostic and Therapeutic Evaluation

Acute Coronary SyndromeMyocardium; Injury
IRCCS Azienda Ospedaliero-Universitaria di Bologna11,000 enrolled3 locationsNCT03883711
Recruiting
Phase 2

Focused Orticumab Research for Treating Inflammation in Coronary Arteries

Heart DiseaseInflammationCoronary Arterial Disease (CAD)+3 more
Abcentra240 enrolled41 locationsNCT06927739
Recruiting
Not Applicable

Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO IV-EPIC 38)

Arterial Occlusive DiseasesCardiovascular DiseasesCoronary Disease+22 more
Fondazione Ricerca e Innovazione Cardiovascolare ETS576 enrolled1 locationNCT06535568
Recruiting
Phase 2

A Polypill for Acute Coronary Syndrome

Acute Coronary Syndrome
University of Texas Southwestern Medical Center1,000 enrolled1 locationNCT07032389
Recruiting
Phase 4

INSIGHTFUL-FFR Clinical Trial

Acute Coronary SyndromeCoronary Artery Disease
CoreAalst BV2,500 enrolled29 locationsNCT05437900