Measurement Of NT-proBNP to Predict Outcomes in Surgery
Peri-operative Measurement of NT-proBNP to Predict Outcomes in Patients Undergoing Elective Vascular Surgery
Norfolk and Norwich University Hospitals NHS Foundation Trust
200 participants
Sep 5, 2019
OBSERVATIONAL
Conditions
Summary
The team is investigating whether N-terminal pro B-type natriuretic peptide (NT-proBNP) and other cardiac markers are useful for predicting outcomes for patients undergoing vascular surgery. By measuring NT-proBNP before and after surgery, the investigators may be able to determine which patients are at risk of an adverse outcome, such as a heart attack or death.
Eligibility
Inclusion Criteria12
- Patients who are equal to or over 18 years old
- Patients scheduled to undergo elective surgery for the following procedures:
- Infrainguinal arterial reconstruction
- Aortic aneurysm
- Aorto-bifemoral bypass / or aortic endarterectomy
- Femoro-popliteal bypass
- Femoro-distal bypass
- Femoral endarterectomy
- Femoro-femoral crossover
- Axillo-femoral bypass
- Elective carotid surgery
- Patients having either general or regional anaesthesia for their surgery
Exclusion Criteria5
- Patients undergoing emergency surgery
- Those who are unable or unwilling to give informed consent
- Patients with unstable coronary syndromes (acute or recent MI with evidence of important ischemic risk by clinical symptoms or stress testing or unstable or severe angina pectoris)
- Patients with decompensated heart failure (new onset shortness of breath and rales together with echocardiographic evidence of cardiac dysfunction or deterioration of chronic heart failure despite heart failure therapy)
- Patients with chronic atrial fibrillation
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04014647