RecruitingPhase 3NCT04028401

Optimization of Skin Preparation to Reduce Cutibacterium Acnes Colonization in Superficial and Deep Samples During Prosthetic Shoulder Surgery in Male Patients


Sponsor

Nantes University Hospital

Enrollment

110 participants

Start Date

Jun 19, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

Infections on joint replacements remain one of the most serious complications of orthopaedic surgery. Despite improvements in skin preparation and antibiotic prophylaxis procedures, the risk of infection of joint prosthesis is still high, particularly for shoulder prostheses, especially in men. One of the bacteria most often involved in post-operative infections for shoulder prosthesis is Cutibacterium acnes (CA). This bacterium is one of the predominant bacteria in pilosebaceous units. Eradication of this micro-organism remains difficult despite the techniques used in the preoperative phase. The objective of this protocol is to evaluate the efficacy of applying a 5% benzoyl peroxide topical during the 5 days preceding the procedure in the surgical skin incision area, which is based on local acne treatment, on the reduction of the CA bacterial load in the dermis of the approach to shoulder arthroplasty in men.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called 5% benzoyl peroxide for people with cutibacterium acnes infection. The study is currently recruiting participants at 6 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG5% benzoyl peroxide

Application of 5% benzoyl peroxide during 5 days before the procedure


Locations(6)

CHU d'Angers

Angers, France

CHU de Brest

Brest, France

CHU de Limoges

Limoges, France

CHU de Nantes

Nantes, France

CHU de Rennes

Rennes, France

CHU de Tours

Tours, France

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NCT04028401