Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD)

This study is testing magnetic seizure therapy (MST) — a newer, more targeted alternative to electroconvulsive therapy (ECT) — in people with bipolar depression or treatment-resistant depression. MST uses a powerful magnetic field to induce a controlled seizure in the brain. Researchers believe it may be as effective as ECT but with fewer memory side effects. **You may be eligible if...** - You have been diagnosed with Bipolar I or II disorder, currently in a depressive episode, OR you have treatment-resistant depression (depression that has not responded to multiple treatments) - A rapid response to treatment is needed due to the severity of your condition - You meet the ICD-10 diagnostic criteria for your condition **You may NOT be eligible if...** - You have medical conditions that make the procedure unsafe (such as metal implants in the head, certain heart conditions, or risk of seizure complications) - You are not a candidate for this type of brain stimulation therapy - Your doctor determines the treatment is not appropriate for you Talk to your doctor to see if this trial is right for you.