RecruitingNCT04111692

A Prospective Observational Study of Foam Sclerotherapy .

A Prospective Observational Study of Foam Sclerotherapy for the Treatment of Symptomatic Kidney or Liver Cysts in Patients With Autosomal Dominant Polycystic Kidney and Liver Disease.


Sponsor

Mayo Clinic

Enrollment

100 participants

Start Date

Nov 6, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

An observational prospective study to determine the impact of foam sclerotherapy of large, dominant kidney/liver cysts on quality of life outcomes and kidney/liver cyst volumes at up to 12 months of follow-up in patients with autosomal dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver disease (ADPLD).


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria4

  • Age ≥18 years
  • Clinical diagnosis of ADPKD or ADPLD
  • large, non-exophytic liver or kidney cyst
  • Compressive symptoms from dominant cyst

Exclusion Criteria7

  • Age \<18 years
  • Absence of ADPKD or ADPLD
  • Largest cyst \<4cm in all 3 dimensions or largest cyst volume \<400cc
  • \>3 large, non-exophytic liver or kidney cyst(s) ≥4cm in all 3 dimensions (cyst volume ≥400cc)
  • Unwilling to comply with study follow-up protocol to 12 ± 1months post-FS
  • Lacking capacity to provide informed consent to FS of liver or kidney cysts
  • Pregnancy

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Locations(1)

Mayo Clinic

Rochester, Minnesota, United States

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NCT04111692


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