RecruitingNCT04114084

Sleep Apnea in Patients With MGUS and MM


Sponsor

Michael Tomasson

Enrollment

200 participants

Start Date

May 23, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

This study involves patients with plasma cell dyscrasia including monoclonal gammopathy of undetermined significance (MGUS) or multiple myeloma (MM), with and without sleep apnea, who are providing bone marrow specimens. Specimens will be obtained at the time that patients undergo a standard-of-care procedure in order to minimize discomfort and reduce any risk.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Inclusion Criteria1

  • Patients diagnosed with MGUS or MM who will be receiving a bone marrow biopsy as part of their standard of care are eligible to participate in this study

Interventions

PROCEDUREBone Marrow Aspirate and Biopsy

The aspirate sample obtained for research at the time a standard-of-care biopsy is taking place will be approximately 40cc. Bone marrow aspiration removes bone marrow fluid and cells through a needle placed into the bone. Usually this sample is taken from the back of the pelvic bone, but it may also be taken from the sternum or the front of the pelvic bone. A bone marrow biopsy removes bone with the marrow inside and is done prior to the aspirate. Each biopsy and aspirate procedure takes approximately 15 minutes total. Bone marrow aspirate may be collected in a separate tube for research or collected from the standard-of-care specimen with left-over aspirate not otherwise needed for clinical purposes, or from previous procedures.


Locations(1)

University of Iowa

Iowa City, Iowa, United States

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NCT04114084


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