RecruitingNot ApplicableNCT04119908

Videomicroscopy for the Prediction of Bleeding in Constitutional Haemorrhagic Diseases

Interest of Sublingual Videomicroscopy for the Prediction of Bleeding in Von Willebrand Disease and Other Constitutional Haemorrhagic Diseases


Sponsor

University Hospital, Lille

Enrollment

400 participants

Start Date

May 24, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

In Willebrand disease, there is currently no test available to identify non-invasively patients with a high risk of bleeding from angiodysplasias The study propose to use a sublingual capillary bed analysis by video-microscopy, a sensitive, reproducible and non-invasive technique, to assess whether sublingual capillary density is predictive of hemorrhagic risk for patients with von Willebrand disease.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Social insured patient

Exclusion Criteria4

  • Minor patient
  • Refusal of consent
  • Person benefiting from a system of legal protection
  • Pregnant patient

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Interventions

DEVICESublingual videomicroscopy

Measurement of sublingual capillary density by video microscopy

BIOLOGICALblood sample

Collection of citrate tubes of 5 mL at baseline and at 36 months


Locations(1)

CHU de Lille

Lille, Nord, France

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NCT04119908


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