RecruitingPhase 3NCT04151472

Idebenone for the Preventive Treatment of Migraine

A Randomized, Double-blinded, Placebo-controlled Trial of Idebenone in the Prevention of Episodic Migraine


Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Enrollment

180 participants

Start Date

Dec 8, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Idebenone improves energy metabolism similarly to Coenzyme Q10, which is effective in migraine prophylaxis. The investigators compare idebenone (90 mg/day, 270 mg/day) and placebo in 180 migraine patients in a double-blind, randomized, placebo-controlled, multicenter trial to study whether Idebenone is superior to placebo in the prevention of episodic migraine with or without aura.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called 270mg Idebenone, a drug called 90mg Idebenone, and others for people with headache disorders and migraine disorders. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPlacebo

Placebo oral tablet, three times a day

DRUG90mg Idebenone

Idebenone 30 MG Oral Tablet, three times a day

DRUG270mg Idebenone

Idebenone 90 MG Oral Tablet, three times a day


Locations(1)

Kaiming Liu

Hangzhou, Zhejiang, China

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NCT04151472


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