Biospecimen Analysis in Detecting Chemical Concentrations in Patients With Chronic or Infectious Diseases Receiving Meditations
Pilot Study to Evaluate Substances in Sweat, Saliva, and Blood
City of Hope Medical Center
100 participants
Nov 9, 2018
OBSERVATIONAL
Conditions
Summary
This trial collects and analyzes sweat and saliva samples compared to blood in detecting chemical concentrations in the body in patients with chronic or infectious diseases receiving medications. Wearable sweat sensors are capable of monitoring electrolytes and metabolites (sodium, potassium, glucose, lactate, etc.) for health monitoring and disease diagnosis. Designing wearable sweat sensors capable of providing information regarding drug administration may be challenging due to ultralow concentrations in biofluids. This trial seeks to determine if the use of a smart wristband can accurately measure the levels of chemicals and substances in sweat.
Eligibility
Inclusion Criteria4
- Scheduled to receive medications including, but not limited to, cyclophosphamide, mycophenolic acid, mycophenolate mofetil, metformin or busulfan (any dose, any number of doses, any dosing frequency) as part of treatment at any time. Patients with chronic or infectious diseases can participate
- Willingness to:
- Provide blood, sweat, and saliva samples
- Permit medical record review
Exclusion Criteria2
- Pilocarpine allergy
- Difficulty with understanding written English
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Undergo collection of sweat, saliva, and blood samples
Review of medical chart
Complete questionnaire
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04160429