5HTP Regulation Of Asthma In Children

This study is testing whether 5-HTP — a natural supplement that the body uses to make serotonin — can help reduce asthma symptoms in children who also have anxiety or depression. Research suggests that mood and asthma are connected through serotonin pathways in the lungs and brain, and this study explores whether 5-HTP might address both. **You may be eligible if...** - You are between 8 and 18 years old - You have mild to moderate asthma - You have a positive allergy test (skin or blood IgE test) - You weigh at least 70 lbs (32 kg) - You score above the cutoff on a standardized anxiety or depression scale (CES-DC or SCARED) **You may NOT be eligible if...** - You are currently taking an SSRI antidepressant - You take a leukotriene inhibitor (like montelukast/Singulair) - You take a biologic medication for asthma (like omalizumab or dupilumab) - You have severe asthma - You have had a previous bad reaction to 5-HTP Talk to your doctor to see if this trial is right for you.