Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome
Identification of Reversible Cerebral Vasoconstriction Syndrome's Precipitating Factors. Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome
University Hospital, Montpellier
225 participants
Dec 5, 2019
INTERVENTIONAL
Conditions
Summary
This study will be the first to evaluate the role played by potential precipitating factors and risk factors in Reversible Cerebral Vasoconstriction Syndrome (RCVS) through of prospective selection of carefully characterised patients and controls. The impact of these factors on the prognosis will be evaluated through a follow-up assessment of patients. Our study will include the formation of a clinicoradiological database and a biobank (plasma, cerebro-spinal fluid, DNA) which will be the tools of a future large multicentre study on RCVS.
Eligibility
Inclusion Criteria10
- For the Patients
- Men and women of 18 and more years old
- Taken care in the CHU of Montpellier
- Diagnosis of SVCR or SVCR without visible vasoconstriction makes in 14 days preceding the inclusion
- According to the consensual criteria of diagnosis and those of the international classification of the headaches ICHD-3
- Informed consent and writes for the participation in the study
- For volunteers
- Men and women of 18 and more, mated in the Cases on the sex and the age
- Patients with an acute pathology not Neurological and not vascular (for example, eye foreign body) OR Healthy Subjects
- Informed written consent and for the participation in the study
Exclusion Criteria4
- Coma, insanity, language barrier or severe aphasia preventing from answering the questions
- Follow-up considered impossible for 3 months (e.g.: priority associated pathology in the care, the transfer(transformation))
- People placed under legal protection
- Refusal to participate in the study
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
We are collecting additional blood and CSF samples for patients (during RCVS episode and after resolution of RCVS episode) and for control subjects to constitute a biobank, in order to compare different biologic parameters between RCVS patients and healthy volunteers. A specific agreement will be asked to patients and control subjects before collection of samples. This is why this study is classified as 'interventional' rather than 'observational'.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04179383