LITT Followed by Hypofractionated RT for Recurrent Gliomas

This study is combining two brain cancer treatments for patients whose glioma (brain tumor) has come back: laser interstitial thermal therapy (LITT — a minimally invasive laser procedure that heats and destroys the tumor) followed by a focused course of radiation therapy. **You may be eligible if...** - You have a brain tumor (glioma, WHO grade II–IV) that has returned or grown after previous treatment - You received radiation therapy as part of your original treatment - You have not had re-irradiation (a second round of radiation) before - Your tumor is 6 cm or smaller on MRI - You are in reasonable health and can undergo both procedures **You may NOT be eligible if...** - Your tumor involves the brainstem - You have very poor neurological function (KPS below 60) - You are pregnant - You have active, uncontrolled infections Talk to your doctor to see if this trial is right for you.