Brain Tumor Clinical Trials

168 recruitingLast updated: June 17, 2026

There are 168 actively recruiting brain tumor clinical trials across 26 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1, Phase 4. Top locations include Boston, Massachusetts, United States, New York, New York, United States, Washington D.C., District of Columbia, United States. Updated daily from ClinicalTrials.gov.


Brain Tumor Trials at a Glance

168 actively recruiting trials for brain tumor are listed on ClinicalTrialsFinder across 6 cities in 26 countries. The largest study group is Not Applicable with 55 trials, with the heaviest enrollment activity in Boston, New York, and Washington D.C.. Lead sponsors running brain tumor studies include Tata Memorial Centre, Northwell Health, and Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta.

Browse brain tumor trials by phase

Treatments under study

About Brain Tumor Clinical Trials

Looking for clinical trials for Brain Tumor? There are currently 75 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Brain Tumor trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Brain Tumor clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 168 trials

Recruiting
Phase 1

Chronic CED of TPT for Recurrent Malignant Glioma

Brain Tumor, RecurrentMalignant Glioma (WHO Grade III or IV)IDH1/IDH2 Mutation
Jeffrey N. Bruce6 enrolled1 locationNCT06666712
Recruiting
Phase 1Phase 2

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

OsteosarcomaEwing SarcomaNeuroblastoma+4 more
Milton S. Hershey Medical Center289 enrolled10 locationsNCT06465199
Recruiting
Phase 1Phase 2

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

CancerBrain Tumor
National Cancer Institute (NCI)96 enrolled1 locationNCT05588141
Recruiting
Phase 2

Study of Olutasidenib and Temozolomide in HGG

Metastatic Brain TumorIDH1 MutationAstrocytoma, Grade IV+16 more
Rigel Pharmaceuticals60 enrolled20 locationsNCT06161974
Recruiting

Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

MeningiomaGliomaPrimary Brain Tumor+1 more
Jona Hattangadi-Gluth300 enrolled1 locationNCT05576103
Recruiting

Targeted Pediatric High-Grade Glioma Therapy

Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+6 more
Nationwide Children's Hospital350 enrolled21 locationsNCT05839379
Recruiting
Phase 1

Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)

Pediatric Solid TumorPediatric Brain Tumor
Washington University School of Medicine20 enrolled1 locationNCT05521984
Recruiting
Not Applicable

Regulating Emotions and Behaviors After Brain Injury

EncephalitisAcquired Brain InjuryMeningitis+3 more
University Hospital, Strasbourg, France77 enrolled1 locationNCT05393492
Recruiting
Not Applicable

Assessment of Early Post-operative Nuclear Imaging in Neurosurgery: a Safety and Feasibility Study in Patients Operated for Glioblastoma

GlioblastomaBrain TumorsBrain Imaging
Beta Emitting Accurate Monitored Systems15 enrolled1 locationNCT07274397
Recruiting
Not Applicable

CONVIVO Endomicroscopy

Brain Tumor
Northwell Health30 enrolled1 locationNCT06087393
Recruiting
Not Applicable

Home-based Vision Rehabilitation Guided by Brain Imaging

Traumatic Brain InjuryBrain TumorStroke+6 more
Georgetown University100 enrolled1 locationNCT07635329
Recruiting

European Prospective Investigation Into Childhood Cancer

Acute Lymphoblastic LeukemiaBrain Tumor
Columbia University1,400 enrolled1 locationNCT05375617
Recruiting
Phase 1Phase 2

Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

CancerBrain TumorBrain Cancer+6 more
Northwell Health67 enrolled1 locationNCT03213002
Recruiting
Phase 1Phase 2

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

Brain TumorBrain CancerGlioblastoma+4 more
Northwell Health33 enrolled1 locationNCT02861898
Recruiting
Phase 2

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+7 more
Nationwide Children's Hospital120 enrolled20 locationsNCT05843253
Recruiting

Spectral Precise Image Study for Brain Tumors

Brain Tumors
Philips Clinical & Medical Affairs Global120 enrolled1 locationNCT07620470
Recruiting
Phase 3

Levetiracetam for Seizure Prevention After Brain Tumor Surgery

Postoperative Seizures After Brain Tumor Surgery
Beijing Tiantan Hospital558 enrolled1 locationNCT07239115
Recruiting
Phase 1

A Study of Sotorasib in People With Brain Tumors

Brain Tumor
Memorial Sloan Kettering Cancer Center16 enrolled7 locationsNCT06807619
Recruiting

Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial Tumors

GlioblastomaMeningiomaGlioma+4 more
Medical University of Warsaw200 enrolled1 locationNCT07411690
Recruiting
Not Applicable

Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures

GlioblastomaMeningiomaGlioma+2 more
Medical University of Warsaw382 enrolled1 locationNCT07413796