RecruitingNot ApplicableNCT04188535

Serial MRI Scans During Radiation Therapy

RELAY: Repeated Magnetic Resonance Imaging Examinations to Analyze and Assess Your Cancer: A Prospective Study on the Use of Serial Magnetic Resonance Imaging in the Assessment of Changes During Treatment With Radiation Therapy

Sponsor

Dana-Farber Cancer Institute

Enrollment

149 participants

Start Date

Jan 15, 2020

Study Type

INTERVENTIONAL

Conditions

Esophageal Cancer Prostate Cancer MRI Radiotherapy Glioblastoma Vulvar Cancer Magnetic Resonance Imaging Pediatric Glioblastoma Multiforme

Summary

This is a phase 1 study to determine the feasibility and utility of using serial magnetic resonance imaging (MRI) to assess treatment response during and after radiation therapy (standard of care cancer treatment) for participants with advanced esophageal cancer, glioblastoma, prostate cancer, vulvar cancer or pediatric glioma. The research study procedures include three MRI scans (one before, one during, and one after standard of care cancer radiation therapy) for participants with advanced esophageal cancer, glioblastoma, prostate cancer, vulvar cancer or pediatric glioma. The research study procedures include: * Screening for eligibility * Three MRI scans

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is using serial MRI scans (multiple scans taken over time) during a course of radiation therapy to understand how tumors change in response to treatment. This information could help doctors personalize radiation plans in real time. **You may be eligible if...** - You are 18 or older - You have been diagnosed with any cancer that requires radiation therapy - You are in reasonably good physical condition (ECOG 0–2) - You are willing to sign an informed consent form **You may NOT be eligible if...** - You have a metal implant or condition that prevents MRI scanning - You have severe claustrophobia - You are pregnant (for certain disease cohorts) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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