RecruitingPhase 4NCT04207931
Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study
Sponsor
Wake Forest University Health Sciences
Enrollment
250 participants
Start Date
Apr 30, 2018
Study Type
INTERVENTIONAL
Conditions
Summary
The objective of this study is to examine photos of CCCA patients taken before and after treatment to compare treatment outcomes between different treatment groups
Eligibility
Sex: FEMALEMin Age: 18 YearsMax Age: 60 Years
Inclusion Criteria3
- African-American women, ages 18-60 years old
- with a clinical diagnosis and biopsy-proven CCCA, with Central Scalp Alopecia Scale severity 1 through 4 will be included in this study
- These subjects will be seen and treated in Wake Forest Baptist Health Dermatology Outpatient Clinic
Exclusion Criteria5
- Patients with other forms of hair loss in addition to CCCA will be excluded
- Other patients to be excluded are those with other forms of inflammatory scalp disease (with the exception of mild seborrheic dermatitis)
- patients who have had topical treatment for CCCA within the past 4 months (including topical steroids, topical minoxidil, or any other topical hair regrowth medication)
- patients who have been on a long-term oral antibiotics for hair loss within the past year
- patients who have undergone more than two rounds of intralesional steroid injections to the scalp in the past one year.
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Interventions
DRUGTopical steroid class I-II
applied once daily - 18 month duration of the study
DRUGTriamcinolone Acetonide
Intralesional Steroid Injection, 7.5mg/cc. max dose of 3 cc. Scalp injections will be administered every 6-8 weeks, for a total of 8 injections.
DRUGDoxycyline
oral antibiotic twice daily for 6 months
DRUGMinoxidil
5% solution or foam started after month 8
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04207931