Thrombus Aspiration in STEMI Patients With High Thrombus Burden
Thrombus Aspiration in Primary Percutaneous Coronary Intervention for STEMI Patients With High Thrombus Burden
Guangdong Provincial People's Hospital
3,838 participants
Aug 30, 2020
INTERVENTIONAL
Conditions
Summary
This is a prospective, multicenter, open-label, randomized, controlled, parallel group study, in which ST-segment Elevation Myocardial Infarction (STEMI) patients with high thrombus burden(TIMI thrombus grade ≥3) are included. Patients are randomized to be treated with or without manual thrombus aspiration(TA) during primary percutaneous coronary intervention(PPCI) by a ratio of 1:1.
Eligibility
Inclusion Criteria4
- Age ≥ 18 years;
- STEMI patients undergoing primary PCI within 12 hours after the onset of symptoms;
- High thrombus burden after guidewire passes the lesion (TIMI thrombus grade ≥3);
- Informed consent must be voluntary;
Exclusion Criteria7
- Haemodynamic instability or cardiogenic shock;
- After thrombolytic therapy;
- The predicted survival time is less than 6 months due to non-cardiac disease;
- History of coronary artery bypass grafting;
- Participate in other researches within 30 days;
- Preoperative gastrointestinal bleeding or contraindications to dual antiplatelet therapy;
- Patients were considered unsuitable by other researchers.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Percutaneous Coronary Intervention with manual aspiration thrombectomy
Percutaneous Coronary Intervention without manual aspiration thrombectomy
Locations(50)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04212494