Pantoprazole in Cisplatin Nephrotoxicity

This study is testing whether pantoprazole (a common over-the-counter stomach acid medication) can protect the kidneys from damage caused by cisplatin, a strong chemotherapy drug frequently used to treat head and neck cancers. Cisplatin is effective but can cause kidney injury as a side effect, and researchers want to see if this simple, widely available medication can reduce that risk. **You may be eligible if...** - You have been diagnosed with head and neck cancer - You are scheduled to receive cisplatin chemotherapy as part of your treatment **You may NOT be eligible if...** - Your kidney function is already significantly reduced (GFR below 59 mL/min) - You have diabetes - Your liver enzymes are elevated more than 3 times above the normal upper limit Talk to your doctor to see if this trial is right for you.