The Role of Proprioceptive Deficits, Psychosocial Factors and Inflammation in Pregnancy-related Pelvic Girdle Pain
The Role of Lumbar Proprioceptive Deficits, Psychosocial Factors and Inflammation in Pregnancy-related Pelvic Girdle Pain: a Follow-up Study in Multiparous Pregnant Women
Hasselt University
192 participants
Jun 1, 2020
INTERVENTIONAL
Summary
A large proportion of pregnant women develop pregnancy-related low back and/or pelvic girdle pain (PPGP), which often does not recover spontaneously postpartum. As a result, 10% of women with PPGP are thus crucial. However, the underlying mechanisms of PPGP are still poorly understood. The main objective of this study is to investigate whether lumbar proprioceptive deficits, a disturbed body perception at the lumbar spine, psychosocial factors (incl. pain-related fear of movement, depression, anxiety and stress) and increased serum concentrations of specific inflammatory mediators are associated with (1) a reduced postural control and (2) the development and/or persistence of PPGP in multiparous women during the first and third trimester of pregnancy, and six weeks and six months postpartum.
Eligibility
Inclusion Criteria7
- Singleton pregnancy
- Pregnant of second child or more than second child
- No current PPGP or did not have PPGP during current pregnancy
- Willing to provide written informed consent
- Age- and BMI- matched to pregnant participants
- Nulliparous
- Willing to provide written informed consent
Exclusion Criteria24
- Pregnant for more than 16 weeks
- Having current PPGP or having had PPGP during the current pregnancy
- History of surgery/major trauma to spine or pelvis
- Surgery/physical trauma to the lower limbs more than two years ago and currently still experiencing symptoms such as pain, instability, or stiffness
- Surgery/physical trauma to the lower limbs less than two years ago
- Specific balance or vestibular disorders
- A medical diagnosis of a rheumatic condition or being under treatment for such a condition by a rheumatologist
- Neurological abnormalities (e.g., peripheral neuropathy)
- Uncorrected visual problems
- Acute ankle problems
- Being on absolute or relative bed rest due to pregnancy-related complications
- Having (had) a formal diagnosis of a psychiatric disorder
- Non-Dutch speaking
- Having low back or pelvic girdle pain at the time of inclusion or in the six months leading up to inclusion
- History of chronic low back or pelvic girdle pain
- History of surgery/major trauma to spine, pelvis and/or lower limbs,
- Specific balance or vestibular disorders
- Spinal deformities
- Rheumatic disease
- Neurological abnormalities
- Acute ankle problems
- (A history of) psychiatric disorders
- Uncorrected visual problems
- Non-Dutch speaking
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Interventions
Behavioral assessment of postural control, lumbar proprioceptive use during postural control, back-specific body perception, psychosocial factors (incl. perceived harmfulness of daily activities, pain-related fear of movement, fear-avoidance beliefs, (pregnancy-related) depression, anxiety and stress, optimism/pessimism, pain coping and coping with stressful life events) and inflammatory mediators
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04226716