RecruitingPhase 4NCT04245436

Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)

Acute, Double-blind, Adaptively Randomized Treatment With Duloxetine or Escitalopram, Followed by Open-label Naturalistic Follow-up.


Sponsor

University of Cincinnati

Enrollment

60 participants

Start Date

Jan 1, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

Acute, double-blind, adaptively randomized treatment with duloxetine or escitalopram, followed by open-label naturalistic follow-up.


Eligibility

Min Age: 12 YearsMax Age: 17 Years

Plain Language Summary

Simplified for easier understanding

This study is testing antidepressant medication in teenagers (ages 12–17) who have anxiety disorders, to find out which treatments work best and for how long they should be taken. **You may be eligible if:** - You are between 12 and 17 years old - You have been diagnosed with generalized anxiety disorder, social anxiety disorder, separation anxiety, or panic disorder - You and your parent or guardian are fluent in English - A caregiver is available to help monitor your safety and medications - You have no significant abnormalities on physical exam **You may NOT be eligible if:** - You are pregnant (a negative pregnancy test is required) - You test positive for drugs on a urine screen - You are not using reliable contraception if sexually active - A responsible caregiver is not available to oversee your participation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDuloxetine

Encapsulated duloxetine 30 mg, 60 mg; once-daily

DRUGEscitalopram

Encapsulated escitalopram 5 mg, 10 mg, 15 mg, 20 mg; once-daily


Locations(1)

University of Cincinnati

Cincinnati, Ohio, United States

View Full Details on ClinicalTrials.gov

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NCT04245436


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