RecruitingPhase 4NCT04248205

Ketamine for Post-operative Analgesia in Hemorrhoidectomy

Intra-operative Use of Ketamine for Post-Operative Analgesia in Patients Undergoing Hemorrhoidectomy: A Prospective, Randomized Controlled Trial.


Sponsor

University of Oklahoma

Enrollment

100 participants

Start Date

Jun 15, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

This is a prospective, randomized study of ketamine versus no ketamine in approximately 100 patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids. The participants will be blinded to which treatment arm they are assigned, because participants will be under anesthesia when the ketamine is administered. The investigators will know whether the participant receives ketamine or not.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria2

  • Adults aged 18-100
  • Undergoing a hemorrhoidectomy for Grade III or IV hemorrhoids.

Exclusion Criteria5

  • Inability to undergo general anesthesia
  • Contraindications to hemorrhoidectomy
  • History of schizophrenia or other hallucinatory psychiatric illnesses
  • History of psychosis
  • Chronic narcotic usage defined as either having a pain contract with a pain management specialist and no narcotic usage for one month prior to hemorrhoidectomy.

Interventions

DRUGKetamine

Standard general anesthesia PLUS ketamine will be given for post-operative analgesia


Locations(1)

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, United States

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NCT04248205


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