Proximal Row Carpectomy vs Four-corner Fusion for Osteoarthritis of the Wrist
A Double-blinded Randomized Controlled Multicenter Trial Comparing Proximal ROw carpectOmy and Four-corner Fusion (PROOF) for Osteoarthritis of the Wrist
Töölö Hospital
84 participants
Oct 1, 2020
INTERVENTIONAL
Conditions
Summary
Study purpose is to compare the outcome after proximal row carpectomy (PRC) vs four-corner fusion (FCA) for SLAC/SNAC II-III type osteoarthritis (OA) in a double-blinded randomized controlled study setting. Patients with radiologically and clinically confirmed OA are randomized (1:1 computer generated sequence with random block size) to two parallel groups and will undergo either PRC or FCA. The study will be patient and assessor blinded. Baseline data is collected preoperatively and is followed by a follow-up visits at 2 and 6 weeks, 3, 6, 12 months, and 5, 10 years after the intervention. Unveiling of the allocation is at 12 months post-intervention.
Eligibility
Plain Language Summary
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Interventions
Excision of the proximal carpal row - the scaphoid, lunate and triquetrum
Scaphoid excision and four-corner fusion with cannulated headless compression screws/dorsal plate
Locations(5)
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NCT04260165