RecruitingNot ApplicableNCT04260165

Proximal Row Carpectomy vs Four-corner Fusion for Osteoarthritis of the Wrist

A Double-blinded Randomized Controlled Multicenter Trial Comparing Proximal ROw carpectOmy and Four-corner Fusion (PROOF) for Osteoarthritis of the Wrist


Sponsor

Töölö Hospital

Enrollment

84 participants

Start Date

Oct 1, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

Study purpose is to compare the outcome after proximal row carpectomy (PRC) vs four-corner fusion (FCA) for SLAC/SNAC II-III type osteoarthritis (OA) in a double-blinded randomized controlled study setting. Patients with radiologically and clinically confirmed OA are randomized (1:1 computer generated sequence with random block size) to two parallel groups and will undergo either PRC or FCA. The study will be patient and assessor blinded. Baseline data is collected preoperatively and is followed by a follow-up visits at 2 and 6 weeks, 3, 6, 12 months, and 5, 10 years after the intervention. Unveiling of the allocation is at 12 months post-intervention.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Four-corner fusion and a procedure called Proximal Row Carpectomy for people with scapholunate advanced collapse and wrist osteoarthritis. The study is currently recruiting participants at 5 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREProximal Row Carpectomy

Excision of the proximal carpal row - the scaphoid, lunate and triquetrum

PROCEDUREFour-corner fusion

Scaphoid excision and four-corner fusion with cannulated headless compression screws/dorsal plate


Locations(5)

Töölö Hospital (Helsinki University Hospital)

Helsinki, Finland

Central Hospital of Central Finland

Jyväskylä, Finland

Kymenlaakso Central Hospital

Kotka, Finland

Tampere University Hospital

Tampere, Finland

Turku University Hospital

Turku, Finland

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NCT04260165


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