RecruitingPhase 1Phase 2NCT04271644
BCMA-Targeted CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma and Plasma Cell Disease
Sponsor
Chongqing Precision Biotech Co., Ltd
Enrollment
80 participants
Start Date
Apr 1, 2019
Study Type
INTERVENTIONAL
Conditions
Summary
This is a single arm study to evaluate the efficacy and safety of BCMA-targeted CAR-T cells therapy for patients with relapsed/refractory Multiple Myeloma.
Eligibility
Min Age: 18 YearsMax Age: 75 Years
Plain Language Summary
Simplified for easier understanding
This study is testing a new type of immune cell therapy called CAR-T cells for people with multiple myeloma (a blood cancer) or related plasma cell diseases that have come back or stopped responding to treatment. The therapy uses a patient's own immune cells, re-engineered in a lab to attack cancer cells.
**You may be eligible if...**
- You have been diagnosed with multiple myeloma or a related plasma cell disease
- Your cancer came back or stopped responding to standard chemotherapy
- Your cancer relapsed after a stem cell transplant
- You are between 18 and 75 years old
- Your cancer cells carry the BCMA protein on their surface
- Your expected survival is at least 3 months
**You may NOT be eligible if...**
- You have serious organ problems that would make treatment unsafe
- You cannot give informed consent
- Your cancer does not have the BCMA marker
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
BIOLOGICALBCMA CAR-T cells
BCMA CAR-T cell therapy
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04271644
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