RecruitingPhase 1Phase 2NCT04271644

BCMA-Targeted CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma and Plasma Cell Disease


Sponsor

Chongqing Precision Biotech Co., Ltd

Enrollment

80 participants

Start Date

Apr 1, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

This is a single arm study to evaluate the efficacy and safety of BCMA-targeted CAR-T cells therapy for patients with relapsed/refractory Multiple Myeloma.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new type of immune cell therapy called CAR-T cells for people with multiple myeloma (a blood cancer) or related plasma cell diseases that have come back or stopped responding to treatment. The therapy uses a patient's own immune cells, re-engineered in a lab to attack cancer cells. **You may be eligible if...** - You have been diagnosed with multiple myeloma or a related plasma cell disease - Your cancer came back or stopped responding to standard chemotherapy - Your cancer relapsed after a stem cell transplant - You are between 18 and 75 years old - Your cancer cells carry the BCMA protein on their surface - Your expected survival is at least 3 months **You may NOT be eligible if...** - You have serious organ problems that would make treatment unsafe - You cannot give informed consent - Your cancer does not have the BCMA marker Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALBCMA CAR-T cells

BCMA CAR-T cell therapy


Locations(1)

920th Hospital of Joint Logistics Support Force

Kunming, Yunnan, China

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NCT04271644


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