RecruitingNCT04273828

Impact of Muscle Degeneration in Chronic Low Back Pain

Impact of Muscle Degeneration in Chronic Ow Back Pain in Patients Undergoing Neural Decompression


Sponsor

Hospital Israelita Albert Einstein

Enrollment

168 participants

Start Date

Apr 6, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

Surgical interventions for the removal of intervertebral disc fragments or to enlarge a narrow spine canal are commonly performed worldwide and are considered efficient. Concomitant low back pain is not uncommon among patients with lumbar nerve compression and neurological symptoms. When present, controversy persists in the literature regarding its ideal management. Although neurological symptoms improve after decompressive surgery, the presence of residual chronic low back pain may worsen satisfaction scores and cause functional disability. The hypothesis of the present study is that the presence of atrophy of the paraspinal and trunk muscles predicts chronic low back pain after lumbar neural decompression. If confirmed, this finding will aid in better planning of physical rehabilitation strategies for this group of patients, as well as a clearer prediction regarding surgical treatment outcomes for patients and health professionals.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • adults 18 years of age and older;
  • with symptoms of lumbosacral neural compression (radiculopathy or neurogenic lameness);
  • failed conservative treatment for at least 6 weeks;
  • undergoing surgery for neural decompression (discectomy and / or foraminotomy and / or hemilaminectomy);
  • with complete pre and postoperative medical records in all evaluations.

Exclusion Criteria4

  • need for lumbar arthrodesis;
  • deep infection requiring surgical cleaning;
  • patients submitted to joint facet rhizotomy;
  • active rheumatologic disease, including seronegative arthropathies.

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Interventions

PROCEDURELumbar decompressive surgery

Patients with lumbar degenerative diseases and symptoms of nerve compression (radiculopathy or neurogenic claudication) who will undergo surgical treatment for neural decompression (discectomy, foraminotomy or laminectomy).


Locations(1)

Hospital Israelita Albert Einstein

São Paulo, São Paulo, Brazil

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NCT04273828


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