Ketogenic Diet for New-Onset Absence Epilepsy
A Prospective, Case-control Evaluation of Ketogenic Dietary Therapy for New-onset Childhood Absence Epilepsy
Johns Hopkins University
40 participants
Aug 10, 2020
INTERVENTIONAL
Conditions
Summary
The ketogenic diet is a medical therapy for epilepsy that is used nearly predominantly for refractory epilepsy (after 2-3 drugs have been tried and failed). However, there is both published evidence for first-line use (infantile spasms, Glut1 deficiency syndrome) and also anecdotal experience (families choosing to change the child's (or the family' own) diet rather than use anticonvulsant medications). Childhood absence epilepsy (refractory) has been published as being responsive to ketogenic diet therapy by the investigators' group previously. This is a small, prospective, 3 month trial to assess if using a modified Atkins diet is a feasible and effective option for new-onset childhood absence epilepsy. The investigators will compare to a group of children in which the parents have declined and chose to start anticonvulsant medications.
Eligibility
Plain Language Summary
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Interventions
Low carb (20g/day), high fat, moderate protein diet. Started as an outpatient in clinic.
At neurologist's discretion. \*OF NOTE\< THIS ARM IS COMPLETED
Locations(1)
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NCT04274179