Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI Study

This study, called HiPPI, tests whether a shorter but higher-dose course of proton radiation therapy (called hypofractionation) works just as well as standard longer courses for treating benign (non-cancerous) brain tumors. Proton therapy is a precise form of radiation that reduces damage to surrounding healthy brain tissue. **You may be eligible if...** - You have been diagnosed with a benign brain or nerve sheath tumor — such as a meningioma, pituitary adenoma, or schwannoma — confirmed by imaging or biopsy - Your doctor recommends fractionated radiation therapy (proton or standard) - You have signed the consent form **You may NOT be eligible if...** - You are pregnant or may become pregnant - There are specific medical reasons you cannot safely receive radiation Talk to your doctor to see if this trial is right for you.