RecruitingNCT04280510

Pathogenic Study of Adult Immune Enteropathies

Sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Enrollment

200 participants

Start Date

Feb 27, 2020

Study Type

OBSERVATIONAL

Conditions

Inflammatory Bowel Diseases Celiac Disease Autoimmune Enteropathy

Summary

The study focuses the mechanisms underlying the loss of intestinal homeostasis in celiac disease, refractory celiac disease and other immune diseases such as monogenic enteropathy, inflammatory bowel diseases or drug induced intestinal diseases. Mechanisms of transformation of lymphocytes leading to onset of lymphomatous complications of immune enteropathies will be investigated. Mechanisms of loss of hepatic lymphocytic homeostasis will also be assessed in liver associated diseases.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study investigates the causes of a condition called immune enteropathy — a disease in which the immune system mistakenly attacks the intestines in adults. Researchers are collecting biological samples and information from patients to better understand what triggers this rare condition. **You may be eligible if...** - You are 18 years or older - You are covered by health/social insurance - You are willing to sign the informed consent form **You may NOT be eligible if...** - You are pregnant - You are under legal guardianship - You are unable to sign informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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