RecruitingNCT04282083

Protocol ITANET - Registry

ITANET -Registry: Multicentric Collection of Cases on Neuroendocrin Gastro-Entero-Pancreatic Tumors (Title in Local Language: ITANET -Registry: Raccolta Multicentrica Dei Casi di Tumore Neuroendocrino Gastro-Entero-Pancreatico)


Sponsor

Italian Association Neuroendocrine Tumors

Enrollment

3,600 participants

Start Date

May 25, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

This is a prospective observational study with the aim to create an Italian database for the collection of data on diagnostic approach, therapy and follow up of patients affected by GEP-NET (gastro-enteric-pancreatic neuroendocrine tumours). Data for approximately 200 italian patients were already previously collected in the ENETS database (international database). ENETS decided to interrupt the collection of the data for an indefinite period. For this reason, through an amendment (number 1) to the protocol, ITANET (Italian Association Neuro-endocrine Tumors) decided to transfer the italian data into a national database and to go on with the collection/update of the data, in order not to lose important clinical information.


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • age\> or = 18 years;
  • histologically/cytologically proved diagnosis of NET OR diagnosis supported by a PET Gallium 68 positivity and by at least a contrastografic imaging of second level (CT scan or NMR);
  • Diagnosis of GEP-NET not antecedent 1 year since the Informed Consent signature;
  • Grading G1, G2, G3 according to the classification WHO 2019;
  • Tumor origin in digestive apparatus (GEP NETs) or tumor of unknown origin;
  • Signed Informed consent.

Exclusion Criteria3

  • Known tumor origin different from digestive apparatus (GEP NETs);
  • no evidence of histologically/cytologically proved diagnosis of NET OR diagnosis supported by a PET Gallium 68 positivity and by at least a contrastografic imaging of second level (CT scan or NMR);
  • Diagnosis of GEP-NET antecedent 1 year since the Informed Consent signature.

Locations(37)

Istituto Clinico Humanitas

Rozzano, Milan, Italy

Clinica Pederzoli

Peschiera del Garda, Verona, Italy

AO Ospedali Riuniti

Ancona, Italy

Azienda Ospedaliera Universitaria Consorziale Policlinico

Bari, Italy

Azienda Ospedaliera Universitaria Policlinico S. Orsola Malpighi

Bologna, Italy

IRCCS Azienda Ospedaliera-Universitaria di Bologna

Bologna, Italy

Ospedale Regionale di Bolzano

Bolzano, Italy

ASST Spedali Civili

Brescia, Italy

Presidio Ospedaliero A. Perrino

Brindisi, Italy

Istituto Oncologico del Mediterraneo

Catania, Italy

Azienda Ospedaliera Universitaria

Ferrara, Italy

Ospedale Policlinico S. Martino

Genova, Italy

Ospedale Santa Maria Goretti

Latina, Italy

Azienda Ospedaliera Universitaria Policlinico G. Martino

Messina, Italy

San Raffaele Hospital

Milan, Italy

IRCCS Istituto Nazionale Tumori

Milan, Italy

Istituto Europeo di Oncologia

Milan, Italy

AOU Policlinico-Modena

Modena, Italy

Ospedale San Gerardo

Monza, Italy

AO Cardarelli

Naples, Italy

Istituto Nazionale Tumori IRCCS Fondazione G. Pascale

Napoli, Italy

Policlinico Università Federico II

Napoli, Italy

Istituto Oncologico Veneto IRCCS

Padua, Italy

Centro di Riferimento Regionale per i Tumori Rari dell'adulto Università degli Studi di Palermo

Palermo, Italy

Ospedale Santa Chiara

Pisa, Italy

AOUSL-IRCCS-Reggio Emilia

Reggio Emilia, Italy

Presidio Ospedaliero di Rho

Rho, Italy

Istituti Fisioterapici Ospitalieri

Roma, Italy

Ospedale San Filippo Neri

Roma, Italy

Policlinico Umberto I

Roma, Italy

Sant'Andrea Hospital

Rome, Italy

Casa Sollievo della Sofferenza

San Giovanni Rotondo, Italy

Azienda Ospedaliera Universitaria

Sassari, Italy

Center for Immuno-Oncology Medical Oncology and Immunotherapy University of Siena

Siena, Italy

Azienda Ospedaliero Universitaria Città della salute e della Scienza

Torino, Italy

Ospedale Santa Chiara

Trento, Italy

Azienda Ospedaliera Universitaria integrata

Verona, Italy

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NCT04282083