RecruitingNCT04291612

Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

SEntinel Lymph Node Endometrial Cancer Trial: A Prospective Multicenter International Single-Arm Observational Trial (SELECT)

Sponsor

Memorial Sloan Kettering Cancer Center

Enrollment

1,715 participants

Start Date

Feb 26, 2020

Study Type

OBSERVATIONAL

Conditions

Endometrial Cancer Endometrioid Adenocarcinoma Endometrial Cancer Stage I

Summary

This study is being done to find out how often endometrial cancer recurs after the standard treatment as well as how often the standard treatment results in a lymphedema.

Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This observational study follows women with endometrial cancer (cancer of the uterus lining) who receive standard treatment — surgery followed by radiation therapy. It collects data to understand how well treatment works and how quality of life is affected over time. **You may be eligible if...** - You are 18 or older - You have been diagnosed with endometrioid adenocarcinoma of the uterus (a common type of uterine cancer) confirmed by biopsy - Your cancer appears confined to the uterus (no spread to lymph nodes or other organs on imaging) - You are in good enough health to undergo surgery (ECOG 0-1 or KPS ≥70%) **You may NOT be eligible if...** - Your cancer has spread outside the uterus - You have suspicious lymph nodes or distant metastases - You are not a candidate for the standard treatment approach Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERPhysical exam

Part 2 participants will be prospectively followed clinically for relapse for 30 months from the date of surgery for physical examination at post-ops visits.

Locations(19)

Hartford Healthcare Cancer Institute @ Hartford Hospital

Hartford, Connecticut, United States

University of Miami (Data Collection Only)

Miami, Florida, United States

Miami Cancer Institute Baptist Health South Florida

Miami, Florida, United States

ADVENTHEALTH (Data collection only)

Orlando, Florida, United States

Mayo Clinic (Data Collection and Data Analysis)

Rochester, Minnesota, United States

Memorial Sloan Kettering Basking Ridge (All protocol activities)

Basking Ridge, New Jersey, United States

Memorial Sloan Kettering Monmouth (All protocol activities)

Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen (All protocol activities)

Montvale, New Jersey, United States

Memorial Sloan Kettering Commack (All Protocol Activities)

Commack, New York, United States

Memorial Sloan Kettering Westchester (All protocol activities)

Harrison, New York, United States

Memorial Sloan Kettering Cancer Center

New York, New York, United States

Memorial Sloan Kettering Nassau (All protocol activities)

Rockville Centre, New York, United States

Lehigh Valley Health Network

Allentown, Pennsylvania, United States

Charles University and General University Hospital (Data Collection Only)

Prague, Czechia

OSPEDALE MICHELE E PIETRO (Data Collection Only)

Ferrera, Italy

UNIVERSITY OF MILANO-BICOCCA, ITALY (Data Collection)

Milan, Italy

FONDAZIONE POLICLINICOUNIVERSITARIO A. GEMELLI, ITALY (Data Collection Only)

Roma, Italy

L'Azienda Sanitaria Universitaria Friuli Centrale

Udine, Italy

OSLO UNIVERSITY HOSPITAL,RIKSHOPITALET (Data Collection Only)

Oslo, Norway

View Full Details on ClinicalTrials.gov

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NCT04291612

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