RecruitingNCT04320264

Metabolic Inflexibility is Related to Elevated Muscle Anaerobic Glycolysis

Sponsor

East Carolina University

Enrollment

100 participants

Start Date

Mar 3, 2020

Study Type

OBSERVATIONAL

Conditions

Metabolic Inflexibility

Summary

The focus of this proposal is on overweight (25\>BMI\<30 kg/m2) subjects, as these individuals exhibit a high risk of becoming obese and/or developing metabolic diseases. We hypothesize that in some overweight individuals there is a "metabolic program" in skeletal muscle which predisposes them to the development of obesity. Findings may lead to clinical screening tools for determining risk for obesity in non-obese individuals and targeting this group for prevention.

Eligibility

Min Age: 18 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Weight loss surgery for people with metabolic inflexibility. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 50 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREWeight loss surgery

Severely obese women (BMI \>40) undergo sleeve gastrectomy

Locations(1)

East Carolina University

Greenville, North Carolina, United States

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NCT04320264