RecruitingPhase 2NCT04322890

Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation

Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation.


Sponsor

Hunan Province Tumor Hospital

Enrollment

6,000 participants

Start Date

Apr 16, 2020

Study Type

INTERVENTIONAL

Summary

The purpose of this study is to assess the Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying the best treatment strategies and survival outcomes for patients with advanced (stage IV) non-small cell lung cancer that carries specific gene mutations (such as EGFR, ALK, or ROS1) that can be targeted with precision medicines. You may be eligible if: you are 18 or older; you have confirmed stage IV non-small cell lung cancer with a targetable gene mutation; your cancer is measurable on scans; your expected survival is at least 12 weeks; and your organ function is adequate. You may NOT be eligible if: your health does not meet the baseline requirements listed above. Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGOsimertinib

Osimertinib 80mg, po, qd;

DRUGAlectinib 150 MG

Alectinib 600mg, po, qd; Lorlatinib, 100mg, po, qd;

DRUGCrizotinib 250 MG

Crizotinib 250 MG po bid.

DRUGSavolitinib, Crizotinib.

Savolitinib, 300mg po qd.

DRUGChemotherapy

500mg, ivgtt, every 21day.


Locations(1)

Yongchang Zhang

Changsha, Hunan, China

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NCT04322890