RecruitingNCT04327570

In-depth Immunological Investigation of COVID-19.

In-depth Characterisation of the Dynamic Host Immune Response to Coronavirus SARS-CoV-2

Sponsor

Universitaire Ziekenhuizen KU Leuven

Enrollment

100 participants

Start Date

Mar 27, 2020

Study Type

OBSERVATIONAL

Conditions

Coronavirus Infections

Summary

The COntAGIouS trial (COvid-19 Advanced Genetic and Immunologic Sampling; an in-depth characterization of the dynamic host immune response to coronavirus SARS-CoV-2) proposes a transdisciplinary approach to identify host factors resulting in hyper-susceptibility to SARS-CoV-2 infection, which is urgently needed for directed medical interventions.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study investigates the immune response to COVID-19 in people who have been hospitalised with a confirmed SARS-CoV-2 infection. By looking in detail at how the immune system responds — including which cells are activated, which antibodies are produced, and how this changes over time — researchers hope to better understand why some patients develop severe disease while others recover quickly. This in-depth immunological data can help in developing better treatments and vaccines for COVID-19 and future pandemics. You may be eligible if: - You are 18 years of age or older - You are hospitalised with PCR-confirmed and/or CT-confirmed COVID-19 infection You may NOT be eligible if: - You are under 18 years of age - You have not given informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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