RecruitingEarly Phase 1NCT04332341

Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation

A Pilot Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation


Sponsor

Case Comprehensive Cancer Center

Enrollment

20 participants

Start Date

May 19, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to find a safe and tolerable way to improve engraftment after transplant. Research studies have shown that adding nicotinamide riboside to donor cells has the potential to increase blood stem cell numbers and potentially decrease the time to engraftment. Also, nicotinamide riboside, TRU NIAGEN (the study drug) is a type of vitamin B supplement that the general public can get without a prescription and is well tolerated.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Nicotinamide riboside (NR) for people with allogeneic hematopoietic cell transplantation. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGNicotinamide riboside (NR)

Nicotinamide riboside, PO, 500mgtwice daily for 21, 28, and 35 days


Locations(1)

Cleveland Clinic, Case Comprehensive Cancer Center

Cleveland, Ohio, United States

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NCT04332341


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