RecruitingNot ApplicableNCT04365751

To Compare the Efficacy of Microwave Ablation and Laparoscopic Hepatectomy for Hepatocellular Carcinoma

A Prospective Multicenter Cohort Control Study of Percutaneous Microwave Ablation and Laparoscopic Resection for Hepatocellular Carcinoma With a Diameter of 3.1 ~ 5.0cm


Sponsor

Chinese PLA General Hospital

Enrollment

1,134 participants

Start Date

Dec 26, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

The study was a prospective multicenter cohort control study, which was divided into 1:1 groups to compare the clinical efficacy of percutaneous microwave ablation and laparoscopic hepatocellular carcinoma resection (tumor diameter 3.1-5.0cm).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two treatments for medium-sized liver tumors (3.1–5.0 cm): microwave ablation (using heat to destroy the tumor from inside) versus laparoscopic surgery (minimally invasive surgical removal). The goal is to find out which approach is safer and more effective for this size of hepatocellular carcinoma (the most common type of liver cancer). **You may be eligible if:** - You are 18 years or older - You have a confirmed diagnosis of liver cancer (hepatocellular carcinoma), either by biopsy or by characteristic imaging patterns on MRI or CT - You have 3 or fewer tumors, with at least one measuring between 3.1 and 5.0 cm - There is no evidence of cancer spread to blood vessels, lymph nodes, or other organs - Your liver function is reasonably preserved (Child-Pugh A or B) **You may NOT be eligible if:** - You have more than 3 tumors - Your largest tumor is outside the 3.1–5.0 cm range - Cancer has spread beyond the liver - Your liver function is severely impaired Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREPercutaneous microwave ablation, Laparoscopic hepatectomy

For patients with hepatocellular carcinoma who meet the enrollment requirements, under the guidance of ultrasound, microwave ablation electrodes were implanted into the tumor tissues by percutaneous puncture, and the high-temperature heat energy was generated to cause coagulation necrosis of the tumor, so as to achieve the goal of local tumor treatment with minimally invasive technology.


Locations(1)

Chinese PLA General Hospital

Beijing, Beijing Municipality, China

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NCT04365751


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