RecruitingNCT04368481

MIDI (MR Imaging Abnormality Deep Learning Identification)

Deep Learning for Identification of Abnormalities on Head MRI


Sponsor

King's College Hospital NHS Trust

Enrollment

30,000 participants

Start Date

Apr 1, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

The study involves the development and testing of an artificial intelligence (AI) tool that can identify abnormalities using patient head scans conducted for routine clinical care and research volunteer scans. A deep learning algorithm will be developed using a dataset of retrospective and prospective MRI head scans to train, validate, and test convolutional networks using software developed at the Department of Biomedical Engineering, King's College London. The reference standard will be consultant radiologist reports of the MRI head scans.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • All head MRI scans with compatible sequences
  • > 18 years old

Exclusion Criteria3

  • No corresponding radiologist report
  • No consent for future use of the research images held within the historic database stored at The Centre for Neuroimaging Sciences (Kings College London).
  • Poor image quality

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Locations(33)

Princess Royal University Hospital, King's College Hospital NHS Foundation Trust

Orpington, Kent, United Kingdom

Buckinghamshire Healthcare Nhs Trust (Stoke Mandeville)

Aylesbury, United Kingdom

Mid and South Essex NHS Foundation Trust

Basildon, United Kingdom

Bedfordshire Hospitals Nhs Foundation Trust

Bedford, United Kingdom

Betsi Cadwaladr University Health Board

Bodelwyddan, United Kingdom

East Kent Hospitals University Nhs Foundation Trust

Canterbury, United Kingdom

South Eastern Health & Social Care Trust

Dundonald, United Kingdom

Queen Victoria Hospital Nhs Foundation Trust

East Grinstead, United Kingdom

Medway Nhs Foundation Trust

Gillingham, United Kingdom

Northern Lincolnshire and Goole Nhs Foundation Trust

Grimsby, United Kingdom

Calderdale and Huddersfield NHS Foundation Trust

Huddersfield, United Kingdom

The Queen Elizabeth Hospital King'S Lynn Nhs Trust

Kings Lynn, United Kingdom

Kingston Hospital Nhs Foundation Trust

Kingston, United Kingdom

NHS FIFE

Kirkcaldy, United Kingdom

Forth Valley Royal Hospital

Larbert, United Kingdom

Leeds Teaching Hospital NHS Trust

Leeds, United Kingdom

University Hospitals of Leicester Nhs Trust

Leicester, United Kingdom

Kings' College Hospital

London, United Kingdom

CNS, Maudsley Hospital, South London and Maudsley NHS Foundation Trust

London, United Kingdom

Croydon University Hospital, Croydon Health Services NHS Trust

London, United Kingdom

Guy's Hospital, Guy's and St Thomas's NHS Foundation Trust

London, United Kingdom

St George's Hospital, St George's University Hospital NHS Foundation Trust

London, United Kingdom

St Thomas' Hospital, Guy's and St Thomas's NHS Foundation Trust

London, United Kingdom

Norfolk and Norwich University Hospitals Nhs Foundation Trust

Norwich, United Kingdom

Queen's Medical Centre University Hospital, Nottingham University Hospitals NHS Foundation Trust

Nottingham, United Kingdom

Surrey and Sussex Healthcare Nhs Trust

Redhill, United Kingdom

East Sussex Healthcare Nhs Trust

Saint Leonards-on-Sea, United Kingdom

Northern Lincolnshire and Goole Nhs Foundation Trust

Scunthorpe, United Kingdom

Mid and South Essex Nhs Foundation Trust

Southend, United Kingdom

St George'S University Hospitals Nhs Foundation Trust

Tooting, United Kingdom

Torbay and South Devon Nhs Foundation Trust

Torquay, United Kingdom

Royal Cornwall Hospitals Nhs Trust

Truro, United Kingdom

West Hertfordshire Hospitals Nhs Trust

Watford, United Kingdom

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