Using Cotyledon Perfusion to Study Drugs Transfer Across the Placenta
Ex Vivo Study of Drugs Transfer Across the Placenta
Assistance Publique - Hôpitaux de Paris
2,000 participants
Jun 5, 2020
OBSERVATIONAL
Conditions
Summary
Drug prescriptions are usual during pregnancy however women and their fetuses still remain an orphan population with regard to drugs efficacy and safety clinical studies. Most xenobiotics diffuse through the placenta and some of them can alter fetus development resulting in structural abnormalities, growth or functional deficiencies. The aim of the study is to study the drug transfer using human placenta after delivery.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Placenta perfusion in double closed circuit, during 3 hours
Locations(1)
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NCT04400084