RecruitingNCT04404114

Shear Wave Elastography in Differentiating Acute or Chronic Kidney Disease


Sponsor

National Taiwan University Hospital

Enrollment

800 participants

Start Date

Feb 1, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

Chronic kidney disease is a common global public health issue and its prevalence increased year by year. Early diagnosis and intervention can prevent further complications and comorbidities of long-term dialysis, cardiovascular events and mortality as well as improve the patients' life quality. To differentiate acute from chronic kidney disease was crucial especially in the setting of crowded and high-risk emergency department. To diagnose acute or chronic kidney disease, physicians usually use blood sample test combined with image studies such as conventional sonography, CT and MRI. However, there was lots of limited factors. The patients may have no previous visit records, poor renal function to receive contrast medium, or critical clinical condition to undergo time-wasting exam. Although the conventional renal sonography is accessible and inexpensive, the judgement is subjective and provide little clinical information. Recent researches of shear wave elastography in evaluating renal parenchymal stiffness showed some correlation with nephropathy. In our study, aiming to facilitating clinical implication, the investigators will use swear-wave elastography combined with conventional renal sonography to benefit patients in diagnosis of acute or chronic kidney disease.


Eligibility

Min Age: 20 Years

Inclusion Criteria1

  • The patients older than 20 years old who needed to receive renal sonography in emergency department of National Taiwan University Hospital.

Exclusion Criteria2

  • The patients who didn't obtain agreement.
  • The patients who can't cooperate or follow the directions

Interventions

DIAGNOSTIC_TESTShear wave elastography to distinguish AKI from normal kidney

Record the patient's kidney size, cortical thickness, possible lesion by ordinary renal sonography as well as cortical elasticity by shear wave elastography

DIAGNOSTIC_TESTShear wave elastography to distinguish AKI from CKD

Record the patient's kidney size, cortical thickness, possible lesion by ordinary renal sonography as well as cortical elasticity by shear wave elastography

DIAGNOSTIC_TESTShear wave elastography to distinguish CKD from normal kidney

Record the patient's kidney size, cortical thickness, possible lesion by ordinary renal sonography as well as cortical elasticity by shear wave elastography


Locations(1)

National Taiwan University Hospital

Taipei, Taiwan

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NCT04404114


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