RecruitingNot ApplicableNCT04416165

Comparison of FDG and FAPI in Patients With Various Types of Cancer


Sponsor

The First Affiliated Hospital of Xiamen University

Enrollment

3,000 participants

Start Date

Oct 20, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate the potential usefulness of 68Ga-DOTA-FAPI-04 positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various types of cancer, compared with 18F-FDG PET/CT.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Inclusion Criteria1

  • (i) adult patients (aged 18 years or order); (ii) patients with suspected or newly diagnosed or previously treated malignant tumors (supporting evidence may include magnetic resonance imaging (MRI), CT, tumor markers and pathology report); (iii) patients who had scheduled both 18F-FDG and 68Ga-DOTA-FAPI-04 PET/CT scans; (iv) patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee.

Exclusion Criteria1

  • (i) patients with non-malignant lesions; (ii) patients with pregnancy; (iii) the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.

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Interventions

DIAGNOSTIC_TEST18F-FDG and 68Ga-DOTA-FAPI -04 PET/CT

Each subject receive a single intravenous injection of 18F-FDG and 68Ga-DOTA-FAPI-04, and undergo PET/CT imaging within the specified time.


Locations(1)

First affiliated hospital of xiamen university

Xiamen, Fujian, China

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NCT04416165


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