RecruitingNCT04427891

Characteristics of Abdominal Fluid in Patients With Diverticulitis Hinchey III or IV

Study of Changes in Abdominal Fluid in Connection With Peritonitis. A Descriptive Study in Patients With Purulent or Fecal Peritonitis.


Sponsor

Sahlgrenska University Hospital

Enrollment

50 participants

Start Date

Sep 21, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Perforated diverticulitis of the colon can be complicated by peritonitis, either purulent or fecal. Both are life threatening conditions requiring emergency surgery. The background in terms of reasons for inflammation (diverticulitis) and perforation to develop is unknown. In this study we focus on specific changes associated with inflammation, both in tissues and of fecal and mucosal microbiota.


Eligibility

Inclusion Criteria3

  • Signs of perforated diverticulitis with peritonitis and decision to perform emergency surgery (Group I)
  • Signs of acute diverticulitis and no decision of emergency surgery (Group II)
  • Patients with colorectal cancer planned for elective surgery (Group III)

Exclusion Criteria2

  • No surgery performed (Group I and III)
  • Withdrawn consent (any group)

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Locations(1)

Sahlgrenska University Hospital/Östra

Gothenburg, Västra Götaland County, Sweden

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NCT04427891