RecruitingPhase 4NCT04432012

A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation

Comparison of Perioperative Intravenous vs Periarticular Dexamethasone vs no Steroid Supplementation in Terms of Post-operative Pain, Function, Nausea, Hospitalization Length, and Risk of Complications in Patients Undergoing Primary Total Knee Arthroplasty for Knee Osteoarthritis - A Randomized Controlled Trial Clinical Study Protocol

Sponsor

Christian Candrian

Enrollment

159 participants

Start Date

Jul 1, 2020

Study Type

INTERVENTIONAL

Conditions

Total Knee Replacement

Summary

We are going to evaluate the difference between perioperative intravenous steroid supplementation, perioperative periarticular steroid supplementation, and standard anaesthesia protocols. We'll evaluate the outcome of patients with knee osteoarthritis who are undergoing Total Knee Arthroplasty to understand which of the three treatments give more benefits to the patient.

Eligibility

Min Age: 50 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Dexamethasone Sodium Phosphate 4 mg/ml intra-articular and a drug called Dexamethasone Sodium Phosphate 4 mg/ml intravenous for people with total knee replacement. The study is currently recruiting participants at 1 location. People eligible for this study include aged 50 Years to 85 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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