A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation

This study is comparing different ways of giving steroid medication to patients after total knee replacement surgery (TKA). Steroids are powerful anti-inflammatory drugs that can help reduce pain and swelling after surgery, but the best way to administer them — by injection into the joint, intravenously, or another route — is not yet clear. The goal is to find out which method provides the best pain control with the fewest side effects. Patients are randomly assigned to one of the administration methods and followed closely after surgery to measure pain levels, swelling, need for additional pain medications, and any complications. Better pain management after knee replacement means faster recovery and better patient outcomes. You may be eligible if: - You are between 50 and 85 years old - You are having a first-time (primary) total knee replacement at the study hospital - You have a BMI between 18.5 and 35 - You are able to give informed consent and follow all study procedures You may NOT be eligible if: - You have a contraindication to steroids - You are having a revision (repeat) knee replacement - You are already on steroid therapy - You are pregnant or breastfeeding - You have uncontrolled diabetes - You have serious other health conditions (ASA class IV) Talk to your doctor to see if this trial is right for you.