Impact of Sinus Surgery on Individuals With Cystic Fibrosis

This study investigates how endoscopic sinus surgery (ESS) affects quality of life and lung function in adults with cystic fibrosis (CF) who also have chronic rhinosinusitis — a persistent sinus inflammation that is very common in CF. Because the sinuses and lungs are connected, treating sinus disease may benefit overall respiratory health. This study compares outcomes in patients who choose surgery versus those who continue with medical management alone. You may be eligible if... - You are 18 years or older with a confirmed diagnosis of cystic fibrosis - You have chronic rhinosinusitis with symptoms persisting despite initial medical treatment - You have been counseled about endoscopic sinus surgery as a treatment option You may NOT be eligible if... - You had endoscopic sinus surgery in the past 12 months - You plan to receive follow-up care elsewhere - You are unable to complete follow-up surveys Talk to your CF care team if you are experiencing persistent sinus symptoms alongside your lung disease. Addressing sinus disease may be an underutilized opportunity to improve your overall respiratory health.